Increased risk for herpetic eye disease in patients with allergic conjunctivitis

Igor Kaiserman; Nadia Kaiserman; Asher Elhayany; Shlomo Vinker

doi:10.1080/02713680600878808

Increased risk for herpetic eye disease in patients with allergic conjunctivitis

Igor Kaiserman, Nadia Kaiserman, Asher Elhayany, Shlomo Vinker

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Purpose: To evaluate the risk of ocular surface herpetic eye disease (osHED) in allergic eye disease. Methods: We calculated the risk for osHED in 11,205 patients on antiallergic ocular topical agents compared with 453,069 controls based on filled prescriptions for topical acyclovir between 2001 and 2003. Results: Significantly more allergic patients, of all age groups, received treatment for osHED (p < 0.01). The age and gender adjusted relative risk for allergic patients to suffer an osHED event was 2.31 (95% CI: 1.84-2.90), raising to 3.55 (95% CI: 2.0-6.4) in patients that filled ≥4 antiallergic prescriptions. Conclusions: Patients treated for allergic eye disease have an increased risk of osHED.

Original language	English
Pages (from-to)	721-725
Number of pages	5
Journal	Current Eye Research
Volume	31
Issue number	9
DOIs	https://doi.org/10.1080/02713680600878808
State	Published - 1 Sep 2006
Externally published	Yes

Keywords

Allergic conjunctivitis
Herpetic eye disease
Prescriptions database

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10.1080/02713680600878808

Cite this

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title = "Increased risk for herpetic eye disease in patients with allergic conjunctivitis",

abstract = "Purpose: To evaluate the risk of ocular surface herpetic eye disease (osHED) in allergic eye disease. Methods: We calculated the risk for osHED in 11,205 patients on antiallergic ocular topical agents compared with 453,069 controls based on filled prescriptions for topical acyclovir between 2001 and 2003. Results: Significantly more allergic patients, of all age groups, received treatment for osHED (p < 0.01). The age and gender adjusted relative risk for allergic patients to suffer an osHED event was 2.31 (95% CI: 1.84-2.90), raising to 3.55 (95% CI: 2.0-6.4) in patients that filled ≥4 antiallergic prescriptions. Conclusions: Patients treated for allergic eye disease have an increased risk of osHED.",

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author = "Igor Kaiserman and Nadia Kaiserman and Asher Elhayany and Shlomo Vinker",

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doi = "10.1080/02713680600878808",

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AU - Kaiserman, Igor

AU - Kaiserman, Nadia

AU - Elhayany, Asher

AU - Vinker, Shlomo

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N2 - Purpose: To evaluate the risk of ocular surface herpetic eye disease (osHED) in allergic eye disease. Methods: We calculated the risk for osHED in 11,205 patients on antiallergic ocular topical agents compared with 453,069 controls based on filled prescriptions for topical acyclovir between 2001 and 2003. Results: Significantly more allergic patients, of all age groups, received treatment for osHED (p < 0.01). The age and gender adjusted relative risk for allergic patients to suffer an osHED event was 2.31 (95% CI: 1.84-2.90), raising to 3.55 (95% CI: 2.0-6.4) in patients that filled ≥4 antiallergic prescriptions. Conclusions: Patients treated for allergic eye disease have an increased risk of osHED.

AB - Purpose: To evaluate the risk of ocular surface herpetic eye disease (osHED) in allergic eye disease. Methods: We calculated the risk for osHED in 11,205 patients on antiallergic ocular topical agents compared with 453,069 controls based on filled prescriptions for topical acyclovir between 2001 and 2003. Results: Significantly more allergic patients, of all age groups, received treatment for osHED (p < 0.01). The age and gender adjusted relative risk for allergic patients to suffer an osHED event was 2.31 (95% CI: 1.84-2.90), raising to 3.55 (95% CI: 2.0-6.4) in patients that filled ≥4 antiallergic prescriptions. Conclusions: Patients treated for allergic eye disease have an increased risk of osHED.

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KW - Herpetic eye disease

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Increased risk for herpetic eye disease in patients with allergic conjunctivitis

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