In situ localization of ACTH receptor-like mRNA in molluscan and human immunocytes

E. Ottaviani; A. Franchini; I. Hanukoglu

doi:10.1007/s000180050133

In situ localization of ACTH receptor-like mRNA in molluscan and human immunocytes

E. Ottaviani, A. Franchini, I. Hanukoglu

Department of Molecular Biology

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27 Scopus citations

Abstract

Adrenocorticotropin hormone (ACTH) receptor-like messenger RNA was localized in molluscan hemocytes and human peripheral blood mononuclear cells by in situ hybridization using a digoxigenin-labelled bovine complementary DNA probe. These findings suggest that the ACTH receptor gene has been highly conserved during evolution. Moreover, these data represent further support for a relationship between the immune and neuroendocrine systems in invertebrates, as documented in our previous studies.

Original language	English
Pages (from-to)	139-142
Number of pages	4
Journal	Cellular and Molecular Life Sciences
Volume	54
Issue number	2
DOIs	https://doi.org/10.1007/s000180050133
State	Published - 1998

Keywords

ACTH receptor-like mRNA
Human
Immunocyte
In situ hybridization
Mollusc

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abstract = "Adrenocorticotropin hormone (ACTH) receptor-like messenger RNA was localized in molluscan hemocytes and human peripheral blood mononuclear cells by in situ hybridization using a digoxigenin-labelled bovine complementary DNA probe. These findings suggest that the ACTH receptor gene has been highly conserved during evolution. Moreover, these data represent further support for a relationship between the immune and neuroendocrine systems in invertebrates, as documented in our previous studies.",

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AB - Adrenocorticotropin hormone (ACTH) receptor-like messenger RNA was localized in molluscan hemocytes and human peripheral blood mononuclear cells by in situ hybridization using a digoxigenin-labelled bovine complementary DNA probe. These findings suggest that the ACTH receptor gene has been highly conserved during evolution. Moreover, these data represent further support for a relationship between the immune and neuroendocrine systems in invertebrates, as documented in our previous studies.

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KW - Human

KW - Immunocyte

KW - In situ hybridization

KW - Mollusc

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In situ localization of ACTH receptor-like mRNA in molluscan and human immunocytes

Abstract

Keywords

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