In situ localization of ACTH receptor-like mRNA in molluscan and human immunocytes

E. Ottaviani, A. Franchini, I. Hanukoglu

Research output: Contribution to journalArticlepeer-review

27 Scopus citations

Abstract

Adrenocorticotropin hormone (ACTH) receptor-like messenger RNA was localized in molluscan hemocytes and human peripheral blood mononuclear cells by in situ hybridization using a digoxigenin-labelled bovine complementary DNA probe. These findings suggest that the ACTH receptor gene has been highly conserved during evolution. Moreover, these data represent further support for a relationship between the immune and neuroendocrine systems in invertebrates, as documented in our previous studies.

Original languageEnglish
Pages (from-to)139-142
Number of pages4
JournalCellular and Molecular Life Sciences
Volume54
Issue number2
DOIs
StatePublished - 1998

Keywords

  • ACTH receptor-like mRNA
  • Human
  • Immunocyte
  • In situ hybridization
  • Mollusc

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