Impact of asymptomatic Clostridioides difficile carriage screening on antibiotic stewardship among hospitalized patients

Mayan Gilboa; Eyal Meltzer; Noam Barda; Yovel Peretz; Itzchak Levi; Ido Cohen; Galia Rahav; Nati Keller; Dafna Yahav; Gili Regev-Yochay

doi:10.1017/ice.2025.10213

Impact of asymptomatic Clostridioides difficile carriage screening on antibiotic stewardship among hospitalized patients

Mayan Gilboa
, Eyal Meltzer
, Noam Barda
, Yovel Peretz
, Itzchak Levi
, Ido Cohen
, Galia Rahav
, Nati Keller
, Dafna Yahav
, Gili Regev-Yochay

Department of Health Systems Management

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

This study evaluated how informing clinicians about Clostridioides difficile (CD) carriage affected antibiotic stewardship. A quasi-experimental pre/post design assessed antibiotic use in carriers versus non-carriers. Clinician awareness was associated with reduced antibiotic use, particularly quinolones, among carriers. Findings suggest screening and targeted education enhance stewardship and reduce high-risk antibiotic use.

Original language	English
Pages (from-to)	944-947
Number of pages	4
Journal	Infection Control and Hospital Epidemiology
Volume	46
Issue number	9
DOIs	https://doi.org/10.1017/ice.2025.10213
State	Published - 1 Sep 2025

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title = "Impact of asymptomatic Clostridioides difficile carriage screening on antibiotic stewardship among hospitalized patients",

abstract = "This study evaluated how informing clinicians about Clostridioides difficile (CD) carriage affected antibiotic stewardship. A quasi-experimental pre/post design assessed antibiotic use in carriers versus non-carriers. Clinician awareness was associated with reduced antibiotic use, particularly quinolones, among carriers. Findings suggest screening and targeted education enhance stewardship and reduce high-risk antibiotic use.",

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AU - Gilboa, Mayan

AU - Meltzer, Eyal

AU - Barda, Noam

AU - Peretz, Yovel

AU - Levi, Itzchak

AU - Cohen, Ido

AU - Rahav, Galia

AU - Keller, Nati

AU - Yahav, Dafna

AU - Regev-Yochay, Gili

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AB - This study evaluated how informing clinicians about Clostridioides difficile (CD) carriage affected antibiotic stewardship. A quasi-experimental pre/post design assessed antibiotic use in carriers versus non-carriers. Clinician awareness was associated with reduced antibiotic use, particularly quinolones, among carriers. Findings suggest screening and targeted education enhance stewardship and reduce high-risk antibiotic use.

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Impact of asymptomatic Clostridioides difficile carriage screening on antibiotic stewardship among hospitalized patients

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