Hypotension and bradycardia in infants after the use of topical brimonidine and beta-blockers

Nils K. Mungan; Thomas W. Wilson; Ken K. Nischal; Gideon Koren; Alex V. Levin

doi:10.1016/S1091-8531(02)42013-7

Hypotension and bradycardia in infants after the use of topical brimonidine and beta-blockers

Nils K. Mungan, Thomas W. Wilson, Ken K. Nischal, Gideon Koren, Alex V. Levin

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29 Scopus citations

Abstract

Brimonidine is a selective alpha-2 adrenergic agonist used to treat glaucoma. There have been several reports of central nervous system depression after its use in infants.(1-4)We observed rapid-onset bradycardia and decreased blood pressure in addition to central nervous system depression in 2 infants who received concomitant topical brimonidine and beta-blockers.

Original language	English
Pages (from-to)	69-70
Number of pages	2
Journal	Journal of AAPOS
Volume	7
Issue number	1
DOIs	https://doi.org/10.1016/S1091-8531(02)42013-7
State	Published - Feb 2003
Externally published	Yes

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10.1016/S1091-8531(02)42013-7

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abstract = "Brimonidine is a selective alpha-2 adrenergic agonist used to treat glaucoma. There have been several reports of central nervous system depression after its use in infants.(1-4)We observed rapid-onset bradycardia and decreased blood pressure in addition to central nervous system depression in 2 infants who received concomitant topical brimonidine and beta-blockers.",

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AU - Wilson, Thomas W.

AU - Nischal, Ken K.

AU - Koren, Gideon

AU - Levin, Alex V.

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AB - Brimonidine is a selective alpha-2 adrenergic agonist used to treat glaucoma. There have been several reports of central nervous system depression after its use in infants.(1-4)We observed rapid-onset bradycardia and decreased blood pressure in addition to central nervous system depression in 2 infants who received concomitant topical brimonidine and beta-blockers.

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Hypotension and bradycardia in infants after the use of topical brimonidine and beta-blockers

Abstract

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