How Significant Is Magnesium In Thermoregulation?

G. Stendig-Lindberg, Y. Shapiro, D. Moran

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


Nine apparently healthy male subjects, mean age 22.8 yr, SD 4.1, free from disease, medication or addiction who gave informed consent, underwent acclimation process in a heat chamber; exposed during 2 h daily for 10 consecutive days to a temperature of 40°C and 40% relative humidity while walking on a treadmill elevated by 3 at a speed of 5 km/h (VO21.2 l-min-1). Serum, mononuclear and erythrocyte magnesium (S-Mg, M-Mg and E-Mg, respectively) were monitored on day 1, 5 and 10 before and after the heat exposure. S-Mg decreased while M-Mg increased after the heat exposures, suggesting a shift of S-Mg to mononuclear cells. The decrease of S-Mg was sustained at the end of the acclimation process. E-Mg increased up to day 5 and decreased gradually approximating the baseline by day 10. Mg appears to play a significant role in heat acclimation.

Original languageEnglish
Pages (from-to)73-85
Number of pages13
JournalJournal of Basic and Clinical Physiology and Pharmacology
Issue number1
StatePublished - 1998
Externally publishedYes


  • erythrocyte
  • heat acclimation
  • magnesium
  • mononuclear
  • serum
  • thermoregulation


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