Hormonal evaluation and autoimmune background in pruritic urticarial papules and plaques of pregnancy

Joseph Alcalay, Arieh Ingber, Batia Kafri, Jacob Segal, Hayuta Kaufmann, Bilha Hazaz, Miriam Sandbank

Research output: Contribution to journalArticlepeer-review

35 Scopus citations

Abstract

There is little insight into the pathogenesis of most of the dermatoses specifically associated with pregnancy. We evaluated the hormonal profile and the autoimmune background in 11 pregnant women with pruritic urticarial papules and plaques of pregnancy. No statistically significant difference was found between the serum levels of the β-subunit of human chorionic gonadotropin, estradiol, cortisol, and urinary estriol of the patients and gestational age-matched control subjects. No autoantibodies were found in the patients' group. We conclude that patients with pruritic urticarial papules and plaques of pregnancy have no hormonal alterations when compared with normal pregnant women and that no known major autoimmune background plays a part in the pathogenesis of the disease.

Original languageEnglish
Pages (from-to)417-420
Number of pages4
JournalAmerican Journal of Obstetrics and Gynecology
Volume158
Issue number2
DOIs
StatePublished - Dec 1988
Externally publishedYes

Keywords

  • Pruritic urticarial papules
  • autoantibodies
  • hormonal profile
  • plaques of pregnancy

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