High levels of antimicrobial coresistance among extended-spectrum-β- lactamase-producing Enterobacteriaceae

Mitchell J. Schwaber; Shiri Navon-Venezia; David Schwartz; Yehuda Carmeli

doi:10.1128/AAC.49.5.2137-2139.2005

High levels of antimicrobial coresistance among extended-spectrum-β- lactamase-producing Enterobacteriaceae

Mitchell J. Schwaber
, Shiri Navon-Venezia
, David Schwartz
, Yehuda Carmeli

Research output: Contribution to journal › Article › peer-review

149 Scopus citations

Abstract

We compared the susceptibility of 312 extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae isolates with that of 1,216 ESBL nonproducers. Of ESBL producers, 25% were susceptible to gentamicin, 30% to trimethoprim-sulfamethoxazole, 41% to ciprofloxacin, and 60% to piperacillin-tazobactam. ESBL nonproducers were more often susceptible to these agents. ESBL-producing Enterobacteriaceae represent a major source of resistance to various antibiotics.

Original language	English
Pages (from-to)	2137-2139
Number of pages	3
Journal	Antimicrobial Agents and Chemotherapy
Volume	49
Issue number	5
DOIs	https://doi.org/10.1128/AAC.49.5.2137-2139.2005
State	Published - May 2005
Externally published	Yes

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10.1128/AAC.49.5.2137-2139.2005

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title = "High levels of antimicrobial coresistance among extended-spectrum-β- lactamase-producing Enterobacteriaceae",

abstract = "We compared the susceptibility of 312 extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae isolates with that of 1,216 ESBL nonproducers. Of ESBL producers, 25\% were susceptible to gentamicin, 30\% to trimethoprim-sulfamethoxazole, 41\% to ciprofloxacin, and 60\% to piperacillin-tazobactam. ESBL nonproducers were more often susceptible to these agents. ESBL-producing Enterobacteriaceae represent a major source of resistance to various antibiotics.",

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AU - Carmeli, Yehuda

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AB - We compared the susceptibility of 312 extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae isolates with that of 1,216 ESBL nonproducers. Of ESBL producers, 25% were susceptible to gentamicin, 30% to trimethoprim-sulfamethoxazole, 41% to ciprofloxacin, and 60% to piperacillin-tazobactam. ESBL nonproducers were more often susceptible to these agents. ESBL-producing Enterobacteriaceae represent a major source of resistance to various antibiotics.

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High levels of antimicrobial coresistance among extended-spectrum-β- lactamase-producing Enterobacteriaceae

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