High levels of antimicrobial coresistance among extended-spectrum-β- lactamase-producing Enterobacteriaceae

Mitchell J. Schwaber, Shiri Navon-Venezia, David Schwartz, Yehuda Carmeli

Research output: Contribution to journalArticlepeer-review

144 Scopus citations

Abstract

We compared the susceptibility of 312 extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae isolates with that of 1,216 ESBL nonproducers. Of ESBL producers, 25% were susceptible to gentamicin, 30% to trimethoprim-sulfamethoxazole, 41% to ciprofloxacin, and 60% to piperacillin-tazobactam. ESBL nonproducers were more often susceptible to these agents. ESBL-producing Enterobacteriaceae represent a major source of resistance to various antibiotics.

Original languageEnglish
Pages (from-to)2137-2139
Number of pages3
JournalAntimicrobial Agents and Chemotherapy
Volume49
Issue number5
DOIs
StatePublished - May 2005
Externally publishedYes

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