Hair Analysis as a Marker for Fetal Exposure to Maternal Smoking

Julia Klein, David Chitayat, Gideon Koren

Research output: Contribution to journalLetterpeer-review

40 Scopus citations

Abstract

To the Editor: Maternal cigarette smoking during pregnancy is associated with fetal risks in the short and long term1,2. Any attempt to understand the effects of maternal smoking on the fetus should include an estimate of the degree of fetal exposure to the constituents of cigarette smoke. To date, no biologic markers have been identified that can assist in such an estimation. We describe the distribution characteristics of nicotine and its metabolite cotinine in maternal and fetal hair. We studied 10 smoking and 11 nonsmoking mothers (mean ages, 19 and 20 years, respectively) in two hospitals in Toronto…

Original languageEnglish
Pages (from-to)66-67
Number of pages2
JournalNew England Journal of Medicine
Volume328
Issue number1
DOIs
StatePublished - 7 Jan 1993
Externally publishedYes

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