Growing antimicrobial resistance of Shigella isolates

Shai Ashkenazi; Itzhak Levy; Vered Kazaronovski; Zmira Samra

doi:10.1093/jac/dkg080

Growing antimicrobial resistance of Shigella isolates

Shai Ashkenazi, Itzhak Levy, Vered Kazaronovski, Zmira Samra

Research output: Contribution to journal › Article › peer-review

129 Scopus citations

Abstract

Appropriate antibiotic treatment of shigellosis depends on identifying resistance patterns. By studying Shigella isolates in central Israel from 1998 to 2000, and comparing with the period 1991-1992, we identified a significantly increased resistance to tetracycline (from 23% to 87%, P < 0.00001), high resistance to trimethoprim-sulfamethoxazole (94%) and ampicillin (85%) and emerging resistance to quinolones (0.5-2%). These data mandate local monitoring of resistance and its consideration in empirical therapy.

Original language	English
Pages (from-to)	427-429
Number of pages	3
Journal	Journal of Antimicrobial Chemotherapy
Volume	51
Issue number	2
DOIs	https://doi.org/10.1093/jac/dkg080
State	Published - 1 Feb 2003
Externally published	Yes

Keywords

Antibiotic therapy
Diarrhoea
Shigellosis

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10.1093/jac/dkg080

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abstract = "Appropriate antibiotic treatment of shigellosis depends on identifying resistance patterns. By studying Shigella isolates in central Israel from 1998 to 2000, and comparing with the period 1991-1992, we identified a significantly increased resistance to tetracycline (from 23\% to 87\%, P < 0.00001), high resistance to trimethoprim-sulfamethoxazole (94\%) and ampicillin (85\%) and emerging resistance to quinolones (0.5-2\%). These data mandate local monitoring of resistance and its consideration in empirical therapy.",

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KW - Antibiotic therapy

KW - Diarrhoea

KW - Shigellosis

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Growing antimicrobial resistance of Shigella isolates

Abstract

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