Growing antimicrobial resistance of Shigella isolates

Shai Ashkenazi, Itzhak Levy, Vered Kazaronovski, Zmira Samra

Research output: Contribution to journalArticlepeer-review

124 Scopus citations


Appropriate antibiotic treatment of shigellosis depends on identifying resistance patterns. By studying Shigella isolates in central Israel from 1998 to 2000, and comparing with the period 1991-1992, we identified a significantly increased resistance to tetracycline (from 23% to 87%, P < 0.00001), high resistance to trimethoprim-sulfamethoxazole (94%) and ampicillin (85%) and emerging resistance to quinolones (0.5-2%). These data mandate local monitoring of resistance and its consideration in empirical therapy.

Original languageEnglish
Pages (from-to)427-429
Number of pages3
JournalJournal of Antimicrobial Chemotherapy
Issue number2
StatePublished - 1 Feb 2003
Externally publishedYes


  • Antibiotic therapy
  • Diarrhoea
  • Shigellosis


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