Fluorescent probes and labels for biomedical applications

Leonid Patsenker, Anatoliy Tatarets, Olga Kolosova, Olena Obukhova, Yevgeniy Povrozin, Iryna Fedyunyayeva, Inna Yermolenko, Ewald Terpetschnig

Research output: Contribution to journalArticlepeer-review

34 Scopus citations


Fluorescence probes and labels have become indispensable tools for clinical diagnostics, high-throughput screening, and other biomedical applications. We have developed several classes of new squaraine-based red and near-infrared (NIR) probes and labels (SETA and Square series), naphthalimide-based fluorescence lifetime dyes (SeTau series), and cyanine- and squaraine-based quenchers (SQ series). This report discusses the spectral and photophysical properties of these new markers. In particular, the red and NIR dyes of the SETA and Square series are extremely bright, with photostabilities that are unmatched by any other dyes in the same spectral region.

Original languageEnglish
Pages (from-to)179-187
Number of pages9
JournalAnnals of the New York Academy of Sciences
StatePublished - May 2008
Externally publishedYes


  • Biological imaging
  • Biomedical probes and labels
  • Lifetime labels
  • Quenchers
  • pH-sensitive dyes


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