Fluorescent probes and labels for biomedical applications

Leonid Patsenker; Anatoliy Tatarets; Olga Kolosova; Olena Obukhova; Yevgeniy Povrozin; Iryna Fedyunyayeva; Inna Yermolenko; Ewald Terpetschnig

doi:10.1196/annals.1430.035

Fluorescent probes and labels for biomedical applications

Leonid Patsenker, Anatoliy Tatarets, Olga Kolosova, Olena Obukhova, Yevgeniy Povrozin, Iryna Fedyunyayeva, Inna Yermolenko, Ewald Terpetschnig

Research output: Contribution to journal › Article › peer-review

34 Scopus citations

Abstract

Fluorescence probes and labels have become indispensable tools for clinical diagnostics, high-throughput screening, and other biomedical applications. We have developed several classes of new squaraine-based red and near-infrared (NIR) probes and labels (SETA and Square series), naphthalimide-based fluorescence lifetime dyes (SeTau series), and cyanine- and squaraine-based quenchers (SQ series). This report discusses the spectral and photophysical properties of these new markers. In particular, the red and NIR dyes of the SETA and Square series are extremely bright, with photostabilities that are unmatched by any other dyes in the same spectral region.

Original language	English
Pages (from-to)	179-187
Number of pages	9
Journal	Annals of the New York Academy of Sciences
Volume	1130
DOIs	https://doi.org/10.1196/annals.1430.035
State	Published - May 2008
Externally published	Yes

Keywords

Biological imaging
Biomedical probes and labels
Lifetime labels
Quenchers
pH-sensitive dyes

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10.1196/annals.1430.035

Cite this

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abstract = "Fluorescence probes and labels have become indispensable tools for clinical diagnostics, high-throughput screening, and other biomedical applications. We have developed several classes of new squaraine-based red and near-infrared (NIR) probes and labels (SETA and Square series), naphthalimide-based fluorescence lifetime dyes (SeTau series), and cyanine- and squaraine-based quenchers (SQ series). This report discusses the spectral and photophysical properties of these new markers. In particular, the red and NIR dyes of the SETA and Square series are extremely bright, with photostabilities that are unmatched by any other dyes in the same spectral region.",

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author = "Leonid Patsenker and Anatoliy Tatarets and Olga Kolosova and Olena Obukhova and Yevgeniy Povrozin and Iryna Fedyunyayeva and Inna Yermolenko and Ewald Terpetschnig",

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AU - Patsenker, Leonid

AU - Tatarets, Anatoliy

AU - Kolosova, Olga

AU - Obukhova, Olena

AU - Povrozin, Yevgeniy

AU - Fedyunyayeva, Iryna

AU - Yermolenko, Inna

AU - Terpetschnig, Ewald

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AB - Fluorescence probes and labels have become indispensable tools for clinical diagnostics, high-throughput screening, and other biomedical applications. We have developed several classes of new squaraine-based red and near-infrared (NIR) probes and labels (SETA and Square series), naphthalimide-based fluorescence lifetime dyes (SeTau series), and cyanine- and squaraine-based quenchers (SQ series). This report discusses the spectral and photophysical properties of these new markers. In particular, the red and NIR dyes of the SETA and Square series are extremely bright, with photostabilities that are unmatched by any other dyes in the same spectral region.

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Fluorescent probes and labels for biomedical applications

Abstract

Keywords

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