First report on a hyperepidemic clone of KPC-3-producing Klebsiella pneumoniae in Israel genetically related to a strain causing outbreaks in the United States

Shiri Navon-Venezia, Azita Leavitt, Mitchell J. Schwaber, J. Kamile Rasheed, Arjun Srinivasan, Jean B. Patel, Yehuda Carmeli, B. Rubinovitch, I. Muskovitch, O. Schwartz-Harari, M. Dan, O. Zimhony, R. Bardenstein, T. Lazarovitch, D. Schwartz, Y. Keness, R. Raz, Z. Shimoni, S. Paikin

Research output: Contribution to journalArticlepeer-review

162 Scopus citations

Abstract

A highly epidemic carbapenem-resistant clone of KPC-3-producing Klebsiella pneumoniae emerged in Israel in 2006, causing a nationwide outbreak. This clone was genetically related to outbreak strains from the United States isolated in 2000 but differed in KPC-carrying plasmids. The threat of the global spread of hyperepidemic, extensively drug-resistant bacterial strains should be recognized and confronted.

Original languageEnglish
Pages (from-to)818-820
Number of pages3
JournalAntimicrobial Agents and Chemotherapy
Volume53
Issue number2
DOIs
StatePublished - Feb 2009
Externally publishedYes

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