Fetal sex and maternal asthma control in pregnancy

Ludmila N. Bakhireva, Michael Schatz, Kenneth Lyons Jones, Carey M. Tucker, Donald J. Slymen, Hillary S. Klonoff-Cohen, Louise Gresham, Diana Johnson, Christina D. Chambers, D. Quinn, D. Vogt, K. Kao, S. Lavigne, J. Brochu, B. Buehler, E. Conover, K. Ormond, C. Chou, Y. Johnson, S. SwercS. Braddock, P. Slusher, L. Robinson, S. Gangell, G. Koren, M. Morreti, L. Wolfe, J. Carey, J. Robertson, J. Polifka, E. Rudy

Research output: Contribution to journalArticlepeer-review

34 Scopus citations


Asthma is a prevalent chronic disorder that might substantially complicate pregnancy. Some recent reports suggest that the presence of a female fetus might be associated with worse maternal asthma symptoms during pregnancy. We tested this hypothesis using the sample of 719 pregnant women with asthma prospectively enrolled in the OTIS study. The presence of a female fetus was associated with a higher incidence of hospitalizations for asthma during pregnancy (OR = 1.84; 95% CI: 1.05; 3.21) independent of maternal age, BMI, ethnicity, smoking, and socioeconomic status. The current study suggests that pregnant asthmatic women carrying a girl might be more susceptible to asthma exacerbations.

Original languageEnglish
Pages (from-to)403-407
Number of pages5
JournalJournal of Asthma
Issue number5
StatePublished - Jun 2008
Externally publishedYes


  • Asthma
  • Asthma control
  • Asthma exacerbation
  • Fetal sex
  • Pregnancy


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