Fetal outcome following intrauterine amantadine exposure

Maurice Levy, Anne Pastuszak, Gideon Koren

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


Amantadine hydrochloride is a well-known antiviral agent that has been used for the prevention of influenza A2, the treatment of Parkinson diseaase, and, more recently, multiple sclerosis. However, very few data exist about its use in pregnant women. We report a 34-year-old woman who had used amantadine to prevent relapse of her multiple sclerosis throughout two of her pregnancies who subsequently delivered two normal infants. We review the available animal data and two other human pregnancy exposure reports.

Original languageEnglish
Pages (from-to)79-81
Number of pages3
JournalReproductive Toxicology
Issue number1
StatePublished - 1991
Externally publishedYes


  • amantadine hydrochloride
  • fetal outcome
  • gestation
  • obstetrics
  • pregnancy


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