Evolution of Resistance to Irinotecan in Cancer Cells Involves Generation of Topoisomerase-Guided Mutations in Non-Coding Genome That Reduce the Chances of DNA Breaks

Santosh Kumar, Valid Gahramanov, Shivani Patel, Julia Yaglom, Lukasz Kaczmarczyk, Ivan A. Alexandrov, Gabi Gerlitz, Mali Salmon-Divon, Michael Y. Sherman

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

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Biochemistry, Genetics and Molecular Biology

Pharmacology, Toxicology and Pharmaceutical Science