Evaluation of a new method for the prevention of neonatal anemia

Ami Balin, Gideon Koren, M. Hasu, Alvin Zipursky

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


Blood sampling for diagnostic purposes is a major cause of neonatal anemia. We propose a new method of blood sampling which preserves the infant’s erythrocytes. Upon drawing of 1.5-ml blood samples, the syringe is centrifuged and erythrocytes are injected back into the circulation. Using rabbits as an experimental model, we documented the efficiency of this method in decreasing the need for foreign blood transfusion. Results of a variety of laboratory tests performed with plasma obtained with the new method were identical to those achieved with whole blood. Subsequent testing did not show increased risk of contamination or bleeding phenomena secondary to heparin load. Red blood cells obtained by centrifugation were mor­phologically normal. This new method may be effective in reducing the need for foreign blood transfusions in neonates.

Original languageEnglish
Pages (from-to)274-275
Number of pages2
JournalPediatric Research
Issue number3
StatePublished - Mar 1989
Externally publishedYes


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