TY - JOUR
T1 - Enzyme replacement therapy in the management of longstanding skeletal and soft tissue salmonella infection in a patient with Gaucher's disease
AU - Margalit, M.
AU - Ash, N.
AU - Zimran, Ari
AU - Halkin, H.
PY - 2002/9/1
Y1 - 2002/9/1
N2 - A splenectomised patient with Gaucher's disease who developed multiple foci of osteomyelitis and soft tissue abcesses, after a severe episode of group C salmonella sepsis, is described. Aggressive antibiotic treatment and surgical drainage had little effect and the patient's condition continued to deteriorate. With initiation of enzyme replacement therapy (ERT) in addition to specific antibiotic treatment, defervescence and gradual healing occurred. Complete resolution of the infection was seen after 15 months. The possible role of ERT in healing bacterial infections in Gaucher's disease is discussed.
AB - A splenectomised patient with Gaucher's disease who developed multiple foci of osteomyelitis and soft tissue abcesses, after a severe episode of group C salmonella sepsis, is described. Aggressive antibiotic treatment and surgical drainage had little effect and the patient's condition continued to deteriorate. With initiation of enzyme replacement therapy (ERT) in addition to specific antibiotic treatment, defervescence and gradual healing occurred. Complete resolution of the infection was seen after 15 months. The possible role of ERT in healing bacterial infections in Gaucher's disease is discussed.
UR - http://www.scopus.com/inward/record.url?scp=0036750481&partnerID=8YFLogxK
U2 - 10.1136/pmj.78.923.564
DO - 10.1136/pmj.78.923.564
M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???
C2 - 12357022
AN - SCOPUS:0036750481
SN - 0032-5473
VL - 78
SP - 564
EP - 565
JO - Postgraduate Medical Journal
JF - Postgraduate Medical Journal
IS - 923
ER -