Enantioselective synthesis and enantiomeric amplification of amino acids under prebiotic conditions

Mindy Levine; Craig Scott Kenesky; Daniel Mazori; Ronald Breslow

doi:10.1021/ol8007099

Enantioselective synthesis and enantiomeric amplification of amino acids under prebiotic conditions

Mindy Levine
, Craig Scott Kenesky
, Daniel Mazori
, Ronald Breslow

Research output: Contribution to journal › Article › peer-review

49 Scopus citations

Abstract

(Chemical Equation Presented) A plausible origin of biomolecular homochirality is advanced, where α-methyl amino acids found on meteorites transfer their chirality in the synthesis of normal amino acids. This asymmetry can be amplified to nearly homochiral levels, thus providing the necessary prerequisite for life to start on this planet and elsewhere in the universe.

Original language	English
Pages (from-to)	2433-2436
Number of pages	4
Journal	Organic Letters
Volume	10
Issue number	12
DOIs	https://doi.org/10.1021/ol8007099
State	Published - 2008
Externally published	Yes

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10.1021/ol8007099

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title = "Enantioselective synthesis and enantiomeric amplification of amino acids under prebiotic conditions",

abstract = "(Chemical Equation Presented) A plausible origin of biomolecular homochirality is advanced, where α-methyl amino acids found on meteorites transfer their chirality in the synthesis of normal amino acids. This asymmetry can be amplified to nearly homochiral levels, thus providing the necessary prerequisite for life to start on this planet and elsewhere in the universe.",

author = "Mindy Levine and Kenesky, \{Craig Scott\} and Daniel Mazori and Ronald Breslow",

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AU - Kenesky, Craig Scott

AU - Mazori, Daniel

AU - Breslow, Ronald

PY - 2008

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N2 - (Chemical Equation Presented) A plausible origin of biomolecular homochirality is advanced, where α-methyl amino acids found on meteorites transfer their chirality in the synthesis of normal amino acids. This asymmetry can be amplified to nearly homochiral levels, thus providing the necessary prerequisite for life to start on this planet and elsewhere in the universe.

AB - (Chemical Equation Presented) A plausible origin of biomolecular homochirality is advanced, where α-methyl amino acids found on meteorites transfer their chirality in the synthesis of normal amino acids. This asymmetry can be amplified to nearly homochiral levels, thus providing the necessary prerequisite for life to start on this planet and elsewhere in the universe.

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JO - Organic Letters

JF - Organic Letters

IS - 12

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Enantioselective synthesis and enantiomeric amplification of amino acids under prebiotic conditions

Abstract

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