TY - JOUR
T1 - Emergence of KPC-2 and KPC-3 in carbapenem-resistant Klebsiella pneumoniae strains in an Israeli hospital
AU - Leavitt, Azita
AU - Navon-Venezia, Shiri
AU - Chmelnitsky, Inna
AU - Schwaber, Mitchell J.
AU - Carmeli, Yehuda
PY - 2007/8
Y1 - 2007/8
N2 - Carbapenem resistance due to KPC has rarely been observed outside the United States. We noticed a sharp increase in carbapenem-resistant Klebsiella pneumoniae strains possessing KPC in Tel Aviv Medical Center from 2004 to 2006. Sixty percent of the isolates belonged to a single clone susceptible only to gentamicin and colistin and carried the blaKPC-3 gene, while almost all other clones carried the blaKPC-2 gene. This rapid dissemination of KPC outside the United States is worrisome.
AB - Carbapenem resistance due to KPC has rarely been observed outside the United States. We noticed a sharp increase in carbapenem-resistant Klebsiella pneumoniae strains possessing KPC in Tel Aviv Medical Center from 2004 to 2006. Sixty percent of the isolates belonged to a single clone susceptible only to gentamicin and colistin and carried the blaKPC-3 gene, while almost all other clones carried the blaKPC-2 gene. This rapid dissemination of KPC outside the United States is worrisome.
UR - http://www.scopus.com/inward/record.url?scp=34547642726&partnerID=8YFLogxK
U2 - 10.1128/AAC.00299-07
DO - 10.1128/AAC.00299-07
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C2 - 17562800
AN - SCOPUS:34547642726
SN - 0066-4804
VL - 51
SP - 3026
EP - 3029
JO - Antimicrobial Agents and Chemotherapy
JF - Antimicrobial Agents and Chemotherapy
IS - 8
ER -