TY - JOUR
T1 - Effects of hyperbaric oxygen therapy on brain perfusion, cognition and behavior in fetal alcohol spectrum disorder—a case study
AU - Koren, Gideon
AU - Golan, Chaim
AU - Suzin, Gil
AU - Berkovich, Matitiahu
AU - Efrati, Shai
N1 - Publisher Copyright:
© The Author(s) 2019. Medical Council on Alcohol and Oxford University Press. All rights reserved.
PY - 2019/5/1
Y1 - 2019/5/1
N2 - A 15-year-old girl diagnosed with FASD underwent 100 courses of hyperbasic oxygen therapy (HBOT). Prior to HBOT, single motion emission compute tomographic begin imaging (SPECT) revealed areas of hypo-perfusion bilaterally in the orbitofrontal region, temporal lobes and right dorsolateral—frontal, as well the medial aspect of the left cerebellum. Following two sets of HBOT treatments (60 plus 40), over 6 months, there was improvement in perfusion to the left cerebellum as well as the right frontal lobe. This was paralleled by improvement in immediate cognitive tests and an increase in functional brain volume. A follow-up 18 months after HBOT showed sustained improvement in attention with no need for methylphenidate, as well as in math skills and writing.
AB - A 15-year-old girl diagnosed with FASD underwent 100 courses of hyperbasic oxygen therapy (HBOT). Prior to HBOT, single motion emission compute tomographic begin imaging (SPECT) revealed areas of hypo-perfusion bilaterally in the orbitofrontal region, temporal lobes and right dorsolateral—frontal, as well the medial aspect of the left cerebellum. Following two sets of HBOT treatments (60 plus 40), over 6 months, there was improvement in perfusion to the left cerebellum as well as the right frontal lobe. This was paralleled by improvement in immediate cognitive tests and an increase in functional brain volume. A follow-up 18 months after HBOT showed sustained improvement in attention with no need for methylphenidate, as well as in math skills and writing.
UR - http://www.scopus.com/inward/record.url?scp=85065116965&partnerID=8YFLogxK
U2 - 10.1093/alcalc/agz009
DO - 10.1093/alcalc/agz009
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C2 - 30801636
AN - SCOPUS:85065116965
SN - 0735-0414
VL - 54
SP - 177
EP - 179
JO - Alcohol and Alcoholism
JF - Alcohol and Alcoholism
IS - 2
ER -