TY - JOUR
T1 - Effects of β-alanine supplementation on the onset of neuromuscular fatigue and ventilatory threshold in women
AU - Stout, J. R.
AU - Cramer, J. T.
AU - Zoeller, R. F.
AU - Torok, D.
AU - Costa, P.
AU - Hoffman, J. R.
AU - Harris, R. C.
AU - O'Kroy, J.
PY - 2007/4
Y1 - 2007/4
N2 - This study examined the effects of 28 days of β-alanine supplementation on the physical working capacity at fatigue threshold (PWC FT), ventilatory threshold (VT), maximal oxygen consumption (V̇O2-MAX), and time-to-exhaustion (TTE) in women. Twenty-two women (age ± SD 27.4 ± 6.1 yrs) participated and were randomly assigned to either the β-alanine (CarnoSyn™) or Placebo (PL) group. Before (pre) and after (post) the supplementation period, participants performed a continuous, incremental cycle ergometry test to exhaustion to determine the PWCFT, VT, V̇O2-MAX, and TTE. There was a 13.9, 12.6 and 2.5% increase (p < 0.05) in VT, PWCFT, and TTE, respectively, for the β-alanine group, with no changes in the PL (p > 0.05). There were no changes for V̇O2-MAX (p > 0.05) in either group. Results of this study indicate that β-alanine supplementation delays the onset of neuromuscular fatigue (PWCFT) and the ventilatory threshold (VT) at submaximal workloads, and increase in TTE during maximal cycle ergometry performance. However, β-alanine supplementation did not affect maximal aerobic power (V̇O2-MAX). In conclusion, β-alanine supplementation appears to improve submaximal cycle ergometry performance and TTE in young women, perhaps as a result of an increased buffering capacity due to elevated muscle carnosine concentrations.
AB - This study examined the effects of 28 days of β-alanine supplementation on the physical working capacity at fatigue threshold (PWC FT), ventilatory threshold (VT), maximal oxygen consumption (V̇O2-MAX), and time-to-exhaustion (TTE) in women. Twenty-two women (age ± SD 27.4 ± 6.1 yrs) participated and were randomly assigned to either the β-alanine (CarnoSyn™) or Placebo (PL) group. Before (pre) and after (post) the supplementation period, participants performed a continuous, incremental cycle ergometry test to exhaustion to determine the PWCFT, VT, V̇O2-MAX, and TTE. There was a 13.9, 12.6 and 2.5% increase (p < 0.05) in VT, PWCFT, and TTE, respectively, for the β-alanine group, with no changes in the PL (p > 0.05). There were no changes for V̇O2-MAX (p > 0.05) in either group. Results of this study indicate that β-alanine supplementation delays the onset of neuromuscular fatigue (PWCFT) and the ventilatory threshold (VT) at submaximal workloads, and increase in TTE during maximal cycle ergometry performance. However, β-alanine supplementation did not affect maximal aerobic power (V̇O2-MAX). In conclusion, β-alanine supplementation appears to improve submaximal cycle ergometry performance and TTE in young women, perhaps as a result of an increased buffering capacity due to elevated muscle carnosine concentrations.
KW - Carnosine
KW - Cycle ergometry
KW - Electromyography
KW - Ergogenic aids
KW - β-Alanine
UR - https://www.scopus.com/pages/publications/34147124170
U2 - 10.1007/s00726-006-0474-z
DO - 10.1007/s00726-006-0474-z
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C2 - 17136505
AN - SCOPUS:34147124170
SN - 0939-4451
VL - 32
SP - 381
EP - 386
JO - Amino Acids
JF - Amino Acids
IS - 3
ER -