Effect of Muscle Oxygenation during Resistance Exercise on Anabolic Hormone Response

Jay R. Hoffman, Joohee Im, Kenneth W. Rundell, Jie Kang, Shoko Nioka, Barry A. Speiring, Ryoto Kime, Britton Chance

Research output: Contribution to journalArticlepeer-review

57 Scopus citations

Abstract

Purpose: The mechanisms that underlie the affect of acute program variables on muscle growth and strength development for strength/power athletes have been of great interest. This investigation examined the affects of two different resistance exercise protocols on muscle oxygenation, and the anabolic hormonal response to such exercise. Methods: Eleven experienced resistance-trained male athletes performed four sets of the squat exercise using either a low-intensity, high-volume (LI; 15 repetitions at 60% one-repetition maximum [1-RM]) or high-intensity, low-volume (HI; 4 repetitions at 90% 1-RM) load. Venous blood samples were obtained before (Pre), immediate (IP), 20- (20P), and 40-min (40P) postexercise. Continuous-wave near-infrared spectroscopy was used to measure oxygen desaturation during exercise. Results: No differences in muscle deoxygenation were seen between LI and HI. However, time-dependent postexercise reoxygenation was significantly different between the two exercise sessions (35.3 ± 17.4 s vs 24.5 ± 14.3 s in LI and HI, respectively). Testosterone and growth hormone (GH) concentrations were significantly elevated from Pre at IP, 20P, and 40P in both LI and HI. GH concentrations were higher (P < 0.05) for LI than at HI at 20P and 40P. Conclusion: Muscle oxygen recovery kinetics appeared to be influenced by differences in the intensity and volume of exercise, and delayed reoxygenation appears to affect the GH response to exercise.

Original languageEnglish
Pages (from-to)1929-1934
Number of pages6
JournalMedicine and Science in Sports and Exercise
Volume35
Issue number11
DOIs
StatePublished - Nov 2003
Externally publishedYes

Keywords

  • Growth hormone
  • Muscle ischemia
  • Near-infrared spectroscopy
  • Testosterone
  • Weight training

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