Abstract
Carnosine and histidine content in the hippocampus of 14-month-old male rats was examined following 30 days of β-alanine supplementation. All animals were provided identical diets; however, 100 mg of β-alanine was mixed with glucomannan (80:20 blend) in the water of β-alanine supplemented animals. Hippocampal carnosine content was significantly greater (p = 0.005) for β-alanine compared with control, while no differences (p = 0.438) were noted in histidine content between groups. Results provide initial evidence that β-alanine supplementation increases carnosine content in the hippocampus of middle-aged rats, without compromising histidine content. β-Alanine supplementation increases hippocampal carnosine content without compromising histidine content in middle-aged rats.
Original language | English |
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Pages (from-to) | 1112-1115 |
Number of pages | 4 |
Journal | Applied Physiology, Nutrition and Metabolism |
Volume | 44 |
Issue number | 10 |
DOIs | |
State | Published - 2019 |
Keywords
- Aging
- Brain
- Dietary intervention
- Health
- Middle-age
- Nutrition