TY - CHAP
T1 - Developmental pharmacology of aminoglycosides and vancomycin
AU - Koren, Gideon
AU - Klein, Julia
AU - Bologa, Monica
N1 - Publisher Copyright:
© 1990 by CRC Press, Inc.
PY - 2018/1/1
Y1 - 2018/1/1
N2 - Aminoglycosides are the most widely used antibiotics in the neonatal intensive care unit for the treatment of Gram-negative septicemia, meningitis, and necrotizing enterocolitis. Later in infancy and childhood, they are used to treat the bacteremia-septicemia of the immunosuppressed and Gram-negative infections complicating cystic fibrosis. The use of vancomycin as an antistaphylococcal agent has emerged recently parallel to the development of staphylococcal resistance against the penicillins.
AB - Aminoglycosides are the most widely used antibiotics in the neonatal intensive care unit for the treatment of Gram-negative septicemia, meningitis, and necrotizing enterocolitis. Later in infancy and childhood, they are used to treat the bacteremia-septicemia of the immunosuppressed and Gram-negative infections complicating cystic fibrosis. The use of vancomycin as an antistaphylococcal agent has emerged recently parallel to the development of staphylococcal resistance against the penicillins.
UR - http://www.scopus.com/inward/record.url?scp=84910802925&partnerID=8YFLogxK
U2 - 10.1201/9781351071529
DO - 10.1201/9781351071529
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AN - SCOPUS:84910802925
SN - 9781315892429
SP - 173
EP - 184
BT - Drug Toxicity and Metabolism in Pediatrics
ER -