TY - JOUR
T1 - Detection of Medium-Sized Polycyclic Aromatic Hydrocarbons via Fluorescence Energy Transfer
AU - Serio, Nicole
AU - Prignano, Lindsey
AU - Peters, Sean
AU - Levine, Mindy
PY - 2014/10
Y1 - 2014/10
N2 - Reported herein is the use of proximity-induced non-covalent energy transfer for the detection of medium-sized polycyclic aromatic hydrocarbons (PAHs). This energy transfer occurs within the cavity of γ-cyclodextrin in various aqueous environments, including human plasma and coconut water. Highly efficient energy transfer was observed, and the efficiency of the energy transfer is independent of the concentration of γ-cyclodextrin used, demonstrating the importance of hydrophobic binding in facilitating such energy transfer. Low limits of detection were also observed for many of the PAHs investigated, which is promising for the development of fluorescence-based detection schemes. © 2014
AB - Reported herein is the use of proximity-induced non-covalent energy transfer for the detection of medium-sized polycyclic aromatic hydrocarbons (PAHs). This energy transfer occurs within the cavity of γ-cyclodextrin in various aqueous environments, including human plasma and coconut water. Highly efficient energy transfer was observed, and the efficiency of the energy transfer is independent of the concentration of γ-cyclodextrin used, demonstrating the importance of hydrophobic binding in facilitating such energy transfer. Low limits of detection were also observed for many of the PAHs investigated, which is promising for the development of fluorescence-based detection schemes. © 2014
UR - http://www.scopus.com/inward/record.url?scp=84906699619&partnerID=8YFLogxK
U2 - 10.1080/10406638.2014.918889
DO - 10.1080/10406638.2014.918889
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AN - SCOPUS:84906699619
SN - 1040-6638
VL - 34
SP - 561
EP - 572
JO - Polycyclic Aromatic Compounds
JF - Polycyclic Aromatic Compounds
IS - 5
ER -