Abstract
The ability to detect human growth hormone (hGH) via sensitive, selective, and easy-to-use methods is a high priority research area from a variety of public health, law enforcement, and scientific objectives. Reported herein is the use of cyclodextrin-promoted fluorescence modulation of a high-quantum yield BODIPY fluorophore in the presence of low concentrations of hGH, leading to a system that can detect hGH in concentrations as low as 0.279 µM and with a 96% accuracy in distinguishing different hGH concentrations.
| Original language | English |
|---|---|
| Pages (from-to) | 1871-1880 |
| Number of pages | 10 |
| Journal | Analytical Letters |
| Volume | 54 |
| Issue number | 11 |
| DOIs | |
| State | Published - 2021 |
Keywords
- BODIPY
- cyclodextrin
- fluorescence spectroscopy
- human growth hormone
- sensors