Data on peptidyl platform-based anticancer drug synthesis and triton-x-based micellar clusters (MCs) self-assembly peculiarities for enhanced solubilization, encapsulation of hydrophobic compounds and their interaction with HeLa cells

Alexey V. Solomonov; Yuriy S. Marfin; Evgeniy V. Rumyantsev; Elena Ragozin; Talia Shekhter Zahavi; Gary Gellerman; Alexander B. Tesler; Falk Muench; Akiko Kumagai; Atsushi Miyawaki

doi:10.1016/j.dib.2019.104052

Data on peptidyl platform-based anticancer drug synthesis and triton-x-based micellar clusters (MCs) self-assembly peculiarities for enhanced solubilization, encapsulation of hydrophobic compounds and their interaction with HeLa cells

Alexey V. Solomonov, Yuriy S. Marfin, Evgeniy V. Rumyantsev, Elena Ragozin, Talia Shekhter Zahavi, Gary Gellerman, Alexander B. Tesler, Falk Muench, Akiko Kumagai, Atsushi Miyawaki

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

The data presented here refer to a research article entitled “Self-Assembled Micellar Clusters Based on Triton-X-family Surfactants for Enhanced Solubilization, Encapsulation, Proteins Permeability Control, and Anticancer Drug Delivery” Solomonov et al., 2019. The present article provides the General Procedure for clusterization of Triton-X-based micelles and the effect of (i) metal ion, surfactant, and chelator concentration on the developed clusters formation, (ii) surfactant-chelator relation change, (iii) metal ion-micelles concertation ratio variation, (iv) metal ion replacement, (v) solvent replacement, (vi) kinetics of clusters formation, (vii) hydrophobic fluorescent dye (Coumarin 6) solubilization in aqueous MCs media, (viii) novel anticancer peptidyl drug synthesis and characterization and (ix) the viability of HeLa cells with and without the presence of drug-free Triton-X-based family MCs. These data provide additional insights useful for understanding all aspects of the micellar clusters formation, optimization, and control.

Original language	English
Article number	104052
Journal	Data in Brief
Volume	25
DOIs	https://doi.org/10.1016/j.dib.2019.104052
State	Published - Aug 2019

Keywords

Anticancer drug synthesis
Encapsulation
Fluorescence enhancement
Micellar clusters
Self-assembly
Surfactants
Triton-X

Access to Document

10.1016/j.dib.2019.104052

Fingerprint

Dive into the research topics of 'Data on peptidyl platform-based anticancer drug synthesis and triton-x-based micellar clusters (MCs) self-assembly peculiarities for enhanced solubilization, encapsulation of hydrophobic compounds and their interaction with HeLa cells'. Together they form a unique fingerprint.

Cite this

Solomonov, A. V., Marfin, Y. S., Rumyantsev, E. V., Ragozin, E., Zahavi, T. S., Gellerman, G., Tesler, A. B., Muench, F., Kumagai, A., & Miyawaki, A. (2019). Data on peptidyl platform-based anticancer drug synthesis and triton-x-based micellar clusters (MCs) self-assembly peculiarities for enhanced solubilization, encapsulation of hydrophobic compounds and their interaction with HeLa cells. Data in Brief, 25, Article 104052. https://doi.org/10.1016/j.dib.2019.104052

@article{296e28b8d7984e97b423a9c58bc77fa3,

title = "Data on peptidyl platform-based anticancer drug synthesis and triton-x-based micellar clusters (MCs) self-assembly peculiarities for enhanced solubilization, encapsulation of hydrophobic compounds and their interaction with HeLa cells",

abstract = "The data presented here refer to a research article entitled “Self-Assembled Micellar Clusters Based on Triton-X-family Surfactants for Enhanced Solubilization, Encapsulation, Proteins Permeability Control, and Anticancer Drug Delivery” Solomonov et al., 2019. The present article provides the General Procedure for clusterization of Triton-X-based micelles and the effect of (i) metal ion, surfactant, and chelator concentration on the developed clusters formation, (ii) surfactant-chelator relation change, (iii) metal ion-micelles concertation ratio variation, (iv) metal ion replacement, (v) solvent replacement, (vi) kinetics of clusters formation, (vii) hydrophobic fluorescent dye (Coumarin 6) solubilization in aqueous MCs media, (viii) novel anticancer peptidyl drug synthesis and characterization and (ix) the viability of HeLa cells with and without the presence of drug-free Triton-X-based family MCs. These data provide additional insights useful for understanding all aspects of the micellar clusters formation, optimization, and control.",

keywords = "Anticancer drug synthesis, Encapsulation, Fluorescence enhancement, Micellar clusters, Self-assembly, Surfactants, Triton-X",

author = "Solomonov, {Alexey V.} and Marfin, {Yuriy S.} and Rumyantsev, {Evgeniy V.} and Elena Ragozin and Zahavi, {Talia Shekhter} and Gary Gellerman and Tesler, {Alexander B.} and Falk Muench and Akiko Kumagai and Atsushi Miyawaki",

note = "Publisher Copyright: {\textcopyright} 2019 The Authors",

year = "2019",

month = aug,

doi = "10.1016/j.dib.2019.104052",

language = "אנגלית",

volume = "25",

journal = "Data in Brief",

issn = "2352-3409",

publisher = "Elsevier Inc.",

}

Solomonov, AV, Marfin, YS, Rumyantsev, EV, Ragozin, E, Zahavi, TS, Gellerman, G, Tesler, AB, Muench, F, Kumagai, A & Miyawaki, A 2019, 'Data on peptidyl platform-based anticancer drug synthesis and triton-x-based micellar clusters (MCs) self-assembly peculiarities for enhanced solubilization, encapsulation of hydrophobic compounds and their interaction with HeLa cells', Data in Brief, vol. 25, 104052. https://doi.org/10.1016/j.dib.2019.104052

Data on peptidyl platform-based anticancer drug synthesis and triton-x-based micellar clusters (MCs) self-assembly peculiarities for enhanced solubilization, encapsulation of hydrophobic compounds and their interaction with HeLa cells. / Solomonov, Alexey V.; Marfin, Yuriy S.; Rumyantsev, Evgeniy V. et al.
In: Data in Brief, Vol. 25, 104052, 08.2019.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Data on peptidyl platform-based anticancer drug synthesis and triton-x-based micellar clusters (MCs) self-assembly peculiarities for enhanced solubilization, encapsulation of hydrophobic compounds and their interaction with HeLa cells

AU - Solomonov, Alexey V.

AU - Marfin, Yuriy S.

AU - Rumyantsev, Evgeniy V.

AU - Ragozin, Elena

AU - Zahavi, Talia Shekhter

AU - Gellerman, Gary

AU - Tesler, Alexander B.

AU - Muench, Falk

AU - Kumagai, Akiko

AU - Miyawaki, Atsushi

PY - 2019/8

Y1 - 2019/8

N2 - The data presented here refer to a research article entitled “Self-Assembled Micellar Clusters Based on Triton-X-family Surfactants for Enhanced Solubilization, Encapsulation, Proteins Permeability Control, and Anticancer Drug Delivery” Solomonov et al., 2019. The present article provides the General Procedure for clusterization of Triton-X-based micelles and the effect of (i) metal ion, surfactant, and chelator concentration on the developed clusters formation, (ii) surfactant-chelator relation change, (iii) metal ion-micelles concertation ratio variation, (iv) metal ion replacement, (v) solvent replacement, (vi) kinetics of clusters formation, (vii) hydrophobic fluorescent dye (Coumarin 6) solubilization in aqueous MCs media, (viii) novel anticancer peptidyl drug synthesis and characterization and (ix) the viability of HeLa cells with and without the presence of drug-free Triton-X-based family MCs. These data provide additional insights useful for understanding all aspects of the micellar clusters formation, optimization, and control.

AB - The data presented here refer to a research article entitled “Self-Assembled Micellar Clusters Based on Triton-X-family Surfactants for Enhanced Solubilization, Encapsulation, Proteins Permeability Control, and Anticancer Drug Delivery” Solomonov et al., 2019. The present article provides the General Procedure for clusterization of Triton-X-based micelles and the effect of (i) metal ion, surfactant, and chelator concentration on the developed clusters formation, (ii) surfactant-chelator relation change, (iii) metal ion-micelles concertation ratio variation, (iv) metal ion replacement, (v) solvent replacement, (vi) kinetics of clusters formation, (vii) hydrophobic fluorescent dye (Coumarin 6) solubilization in aqueous MCs media, (viii) novel anticancer peptidyl drug synthesis and characterization and (ix) the viability of HeLa cells with and without the presence of drug-free Triton-X-based family MCs. These data provide additional insights useful for understanding all aspects of the micellar clusters formation, optimization, and control.

KW - Anticancer drug synthesis

KW - Encapsulation

KW - Fluorescence enhancement

KW - Micellar clusters

KW - Self-assembly

KW - Surfactants

KW - Triton-X

UR - http://www.scopus.com/inward/record.url?scp=85066610593&partnerID=8YFLogxK

U2 - 10.1016/j.dib.2019.104052

DO - 10.1016/j.dib.2019.104052

M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???

AN - SCOPUS:85066610593

SN - 2352-3409

VL - 25

JO - Data in Brief

JF - Data in Brief

M1 - 104052

ER -

Solomonov AV, Marfin YS, Rumyantsev EV, Ragozin E, Zahavi TS, Gellerman G et al. Data on peptidyl platform-based anticancer drug synthesis and triton-x-based micellar clusters (MCs) self-assembly peculiarities for enhanced solubilization, encapsulation of hydrophobic compounds and their interaction with HeLa cells. Data in Brief. 2019 Aug;25:104052. doi: 10.1016/j.dib.2019.104052

Data on peptidyl platform-based anticancer drug synthesis and triton-x-based micellar clusters (MCs) self-assembly peculiarities for enhanced solubilization, encapsulation of hydrophobic compounds and their interaction with HeLa cells

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this