Cyclodextrin-Promoted Detection of Aromatic Toxicants and Toxicant Metabolites in Urine

Dana J. DiScenza, Lauren Gareau, Nicole Serio, John Roque, Lindsey Prignano, Molly Verderame, Mindy Levine

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


Reported herein is the development of a fluorescence-based detection method for aromatic toxicants and toxicant metabolites in urine, using cyclodextrin-promoted energy transfer to high quantumyield fluorophores. This method distinguishes smoker urine from non-smoker urine, enables highly accurate analyte identification, and leads to micromolar detection limits.

Original languageEnglish
Pages (from-to)345-353
Number of pages9
JournalAnalytical Chemistry Letters
Issue number4
StatePublished - 2016
Externally publishedYes


  • Cyclodextrin
  • fluorescence spectroscopy
  • polycyclic aromatic hydrocarbons


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