Corticosteroids-salicylate interaction in a case of juvenile rheumatoid arthritis

Gideon Koren; Chaim Roifman; Erwin Gelfand; Sasson Lavi; David Suria; Leonard Stein

doi:10.1097/00007691-198706000-00009

Corticosteroids-salicylate interaction in a case of juvenile rheumatoid arthritis

Gideon Koren
, Chaim Roifman
, Erwin Gelfand
, Sasson Lavi
, David Suria
, Leonard Stein

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

In an 11-year-old child with juvenile rheumatoid arthritis (JRA), the addition of prednisone caused a significant decrease in salicylate serum concentrations. A pharmacokinetic assessment suggested that these changes were not the result of altered compliance or impaired absorption of salicylate but rather an increase in salicylate clearance induced by the corticosteroid.

Original language	English
Pages (from-to)	177-179
Number of pages	3
Journal	Therapeutic Drug Monitoring
Volume	9
Issue number	2
DOIs	https://doi.org/10.1097/00007691-198706000-00009
State	Published - Jun 1987
Externally published	Yes

Keywords

Corticosteroid
Juvenile rheumatoid arthritis
Prednisone
Salicylate

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10.1097/00007691-198706000-00009

Cite this

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abstract = "In an 11-year-old child with juvenile rheumatoid arthritis (JRA), the addition of prednisone caused a significant decrease in salicylate serum concentrations. A pharmacokinetic assessment suggested that these changes were not the result of altered compliance or impaired absorption of salicylate but rather an increase in salicylate clearance induced by the corticosteroid.",

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AU - Suria, David

AU - Stein, Leonard

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KW - Juvenile rheumatoid arthritis

KW - Prednisone

KW - Salicylate

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Corticosteroids-salicylate interaction in a case of juvenile rheumatoid arthritis

Abstract

Keywords

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