Abstract
In an 11-year-old child with juvenile rheumatoid arthritis (JRA), the addition of prednisone caused a significant decrease in salicylate serum concentrations. A pharmacokinetic assessment suggested that these changes were not the result of altered compliance or impaired absorption of salicylate but rather an increase in salicylate clearance induced by the corticosteroid.
Original language | English |
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Pages (from-to) | 177-179 |
Number of pages | 3 |
Journal | Therapeutic Drug Monitoring |
Volume | 9 |
Issue number | 2 |
DOIs | |
State | Published - Jun 1987 |
Externally published | Yes |
Keywords
- Corticosteroid
- Juvenile rheumatoid arthritis
- Prednisone
- Salicylate