Corticosteroids-salicylate interaction in a case of juvenile rheumatoid arthritis

Gideon Koren, Chaim Roifman, Erwin Gelfand, Sasson Lavi, David Suria, Leonard Stein

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


In an 11-year-old child with juvenile rheumatoid arthritis (JRA), the addition of prednisone caused a significant decrease in salicylate serum concentrations. A pharmacokinetic assessment suggested that these changes were not the result of altered compliance or impaired absorption of salicylate but rather an increase in salicylate clearance induced by the corticosteroid.

Original languageEnglish
Pages (from-to)177-179
Number of pages3
JournalTherapeutic Drug Monitoring
Issue number2
StatePublished - Jun 1987
Externally publishedYes


  • Corticosteroid
  • Juvenile rheumatoid arthritis
  • Prednisone
  • Salicylate


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