TY - JOUR
T1 - Comparison of low- and high-intensity resistance exercise on lipid peroxidation
T2 - Role of muscle oxygenation
AU - Hoffman, Jay R.
AU - Im, Joohee
AU - Kang, Jie
AU - Maresh, Carl M.
AU - Kraemer, William J.
AU - French, Duncan
AU - Nioka, Shoko
AU - Kime, Ryotaro
AU - Rundell, Kenneth W.
AU - Ratamess, Nicholas A.
AU - Faigenbaum, Avery D.
AU - Chance, Britton
N1 - Funding Information:
Authors acknowledge support from RFBR (grants nos. 14-05-00049, 14-05-93090, 15-35-20022, 15-05-01310, 15-55-20004, and 17-05-00001) and NORRUSS program of the Norwegian Research Council (grant no. 233646). V. Tcheverda was partially supported by the Ministry of Education and Science of Kazakhstan Republic under grant 1771/GF4. The simulations were performed on the cluster NKS-30T of the Siberian Supercomputer Centre and Lomonosov Supercomputer of MSU.
PY - 2007/2
Y1 - 2007/2
N2 - The purpose of this study was to examine the effect of low- vs. high-intensity resistance exercise on lipid peroxidation. In addition, the role of muscle oxygenation on plasma malondialdehyde (MDA) concentrations was explored. Eleven experienced resistance trained male athletes (age: 20.8 ± 1.3 years; weight: 96.2 ± 14.4 kg; height: 182.4 ± 7.3 cm) performed 4 sets of the squat exercise using either a low-intensity, high-volume (LI; 15 repetitions at 60% 1 repetition maximum [1RM]) or high-intensity, low-volume (HI; 4 repetitions at 90% 1RM load). Venous blood samples were obtained before the exercise (PRE), immediately following the exercise (IP), and 20 (20P) and 40 minutes (40P) postexercise. Continuous wave near-infrared spectroscopy was used to measure muscle deoxygenation in the vastus lateralis during exercise. Deoxygenated Hb/Mb change was used to determine reoxygenation rate during recovery. No difference in MDA concentrations was seen between LI and HI at any time. Significant correlations were observed between plasma MDA concentrations at IP and the half-time recovery (T1/2 recovery) of muscle reoxygenation (r = 0.45) and between T1/2 recovery and the area under the curve for MDA concentrations (r = 0.44). Results suggest that increases in MDA occur independently of exercise intensity, but tissue acidosis may have a larger influence on MDA formation.
AB - The purpose of this study was to examine the effect of low- vs. high-intensity resistance exercise on lipid peroxidation. In addition, the role of muscle oxygenation on plasma malondialdehyde (MDA) concentrations was explored. Eleven experienced resistance trained male athletes (age: 20.8 ± 1.3 years; weight: 96.2 ± 14.4 kg; height: 182.4 ± 7.3 cm) performed 4 sets of the squat exercise using either a low-intensity, high-volume (LI; 15 repetitions at 60% 1 repetition maximum [1RM]) or high-intensity, low-volume (HI; 4 repetitions at 90% 1RM load). Venous blood samples were obtained before the exercise (PRE), immediately following the exercise (IP), and 20 (20P) and 40 minutes (40P) postexercise. Continuous wave near-infrared spectroscopy was used to measure muscle deoxygenation in the vastus lateralis during exercise. Deoxygenated Hb/Mb change was used to determine reoxygenation rate during recovery. No difference in MDA concentrations was seen between LI and HI at any time. Significant correlations were observed between plasma MDA concentrations at IP and the half-time recovery (T1/2 recovery) of muscle reoxygenation (r = 0.45) and between T1/2 recovery and the area under the curve for MDA concentrations (r = 0.44). Results suggest that increases in MDA occur independently of exercise intensity, but tissue acidosis may have a larger influence on MDA formation.
KW - Athletes
KW - Malondialdehyde
KW - Near-infrared spectroscopy
KW - Oxidative stress
KW - Weight training
UR - http://www.scopus.com/inward/record.url?scp=33947658408&partnerID=8YFLogxK
U2 - 10.1519/00124278-200702000-00022
DO - 10.1519/00124278-200702000-00022
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C2 - 17313297
AN - SCOPUS:33947658408
SN - 1064-8011
VL - 21
SP - 118
EP - 122
JO - Journal of Strength and Conditioning Research
JF - Journal of Strength and Conditioning Research
IS - 1
ER -