TY - JOUR
T1 - Community-associated methicillin-resistant staphylococcus aureus infections in israel*
AU - Nevet, Alon
AU - Ashkenazi, Shai
AU - Samra, Zmira
AU - Livni, Gilat
PY - 2010/7
Y1 - 2010/7
N2 - Background: Community-associated methicillin-resistant Staphylococcus aureus infections are increasingly being documented worldwide. In Israel, however, CA-MRSA infections have not yet been reported, so awareness among physicians may be low. Objective: To alert physicians to the possibility of CA-MRSA infection, which necessitates a distinct therapeutic approach. methods: We present three children with soft tissue infections caused by CA-MRSA who were treated in our medical center from January to March 2009. Results: In all three cases CA-MRSA was identifed as the causative pathogen after surgical or spontaneous drainage. On susceptibility testing, the organisms were resistant to beta-lactam antibiotics but susceptible to clindamycin, rifampicin and trimethoprim-sulfamethoxazole. Conclusions: Physicians should maintain an index of suspicion for CA-MRSA infections. The antibiotic-resistance profle of S. aureus should be watched carefully, and in particular, cultures should be obtained whenever soft tissue infections fail to respond to conventional treatment.
AB - Background: Community-associated methicillin-resistant Staphylococcus aureus infections are increasingly being documented worldwide. In Israel, however, CA-MRSA infections have not yet been reported, so awareness among physicians may be low. Objective: To alert physicians to the possibility of CA-MRSA infection, which necessitates a distinct therapeutic approach. methods: We present three children with soft tissue infections caused by CA-MRSA who were treated in our medical center from January to March 2009. Results: In all three cases CA-MRSA was identifed as the causative pathogen after surgical or spontaneous drainage. On susceptibility testing, the organisms were resistant to beta-lactam antibiotics but susceptible to clindamycin, rifampicin and trimethoprim-sulfamethoxazole. Conclusions: Physicians should maintain an index of suspicion for CA-MRSA infections. The antibiotic-resistance profle of S. aureus should be watched carefully, and in particular, cultures should be obtained whenever soft tissue infections fail to respond to conventional treatment.
KW - Antibiotic resistance
KW - Clindamycin
KW - Soft tissue infection
KW - Staphylococcus aureus
KW - Vancomycin
UR - http://www.scopus.com/inward/record.url?scp=77955072963&partnerID=8YFLogxK
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C2 - 20862825
AN - SCOPUS:77955072963
SN - 1565-1088
VL - 12
SP - 428
EP - 430
JO - Israel Medical Association Journal
JF - Israel Medical Association Journal
IS - 7
ER -