Communicating pharmacogenetic research results to breastfeeding mothers taking codeine: A pilot study of perceptions and benefits

P. Madadi; Y. Joly; D. Avard; D. C. Chitayat; M. A. Smith; C. J.D. Ross; B. C. Carleton; M. R. Hayden; G. Koren

doi:10.1038/clpt.2010.125

Communicating pharmacogenetic research results to breastfeeding mothers taking codeine: A pilot study of perceptions and benefits

P. Madadi, Y. Joly, D. Avard, D. C. Chitayat, M. A. Smith, C. J.D. Ross, B. C. Carleton, M. R. Hayden, G. Koren

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Abstract

Sixty-two codeine-prescribed breastfeeding mothers from a pharmacogenetic study were interviewed regarding the communication of individual CYP2D6 genotype results and overall research findings. All participants wanted to receive the results of their individual genetic tests; however, individuals placed different values on the usefulness of this information toward future medical decisions. Receiving one's pharmacogenetic test results was not associated with a negative psychosocial impact. Thirty-three percent of the participants wished to withhold these results from their physicians. Participants' expectations seem to dictate the extent of transparency of pharmacogenetic research results.

Original language	English
Pages (from-to)	792-795
Number of pages	4
Journal	Clinical Pharmacology and Therapeutics
Volume	88
Issue number	6
DOIs	https://doi.org/10.1038/clpt.2010.125
State	Published - Dec 2010
Externally published	Yes

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10.1038/clpt.2010.125

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abstract = "Sixty-two codeine-prescribed breastfeeding mothers from a pharmacogenetic study were interviewed regarding the communication of individual CYP2D6 genotype results and overall research findings. All participants wanted to receive the results of their individual genetic tests; however, individuals placed different values on the usefulness of this information toward future medical decisions. Receiving one's pharmacogenetic test results was not associated with a negative psychosocial impact. Thirty-three percent of the participants wished to withhold these results from their physicians. Participants' expectations seem to dictate the extent of transparency of pharmacogenetic research results.",

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AU - Joly, Y.

AU - Avard, D.

AU - Chitayat, D. C.

AU - Smith, M. A.

AU - Ross, C. J.D.

AU - Carleton, B. C.

AU - Hayden, M. R.

AU - Koren, G.

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Communicating pharmacogenetic research results to breastfeeding mothers taking codeine: A pilot study of perceptions and benefits

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