Abstract
From a pharmacotherapy perspective, the process of development and growth represents an unstable and dynamic condition. Age-related changes in drug absorption, distribution, and metabolism among neonates, infants, and prepubescent children create a unique situation that may increase drug toxicity of some agents and protect from toxicity of other agents. Understanding the age-related changes in drug disposition that are relevant for therapeutic response and toxicity is essential for optimizing pharmacotherapy at different stages of childhood.
| Original language | English |
|---|---|
| Pages (from-to) | 423-428 |
| Number of pages | 6 |
| Journal | Pediatrics in Review |
| Volume | 19 |
| Issue number | 12 |
| DOIs | |
| State | Published - Dec 1998 |
| Externally published | Yes |
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