TY - JOUR
T1 - Clinical and Socio-Demographic Variables Associated with the Diagnosis of Long COVID Syndrome in Youth
T2 - A Population-Based Study
AU - Merzon, Eugene
AU - Weiss, Margaret
AU - Krone, Beth
AU - Cohen, Shira
AU - Ilani, Gili
AU - Vinker, Shlomo
AU - Cohen-Golan, Avivit
AU - Green, Ilan
AU - Israel, Ariel
AU - Schneider, Tzipporah
AU - Ashkenazi, Shai
AU - Weizman, Abraham
AU - Manor, Iris
N1 - Publisher Copyright:
© 2022 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2022/5/1
Y1 - 2022/5/1
N2 - This study examines the demographic, clinical and socioeconomic factors associated with diagnosis of long COVID syndrome (LCS). Data of 20,601 COVID-19-positive children aged 5 to 18 years were collected between 2020 and 2021 in an Israeli database. Logistic regression analysis was used to evaluate the adjusted odds ratio for the characteristics of the COVID-19 infection and pre-COVID-19 morbidities. Children with LCS were significantly more likely to have been severely symptomatic, required hospitalization, and experienced recurrent acute infection within 180 days. In addition, children with LCS were significantly more likely to have had ADHD, chronic urticaria, and allergic rhinitis. Diagnosis of LCS is significantly associated with pre-COVID-19 ADHD diagnosis, suggesting clinicians treating ADHD children who become infected with COVID-19 remain vigilant for the possibility of LCS. Although the risk of severe COVID-19 infection and LCS in children is low, further research on possible morbidity related to LCS in children is needed.
AB - This study examines the demographic, clinical and socioeconomic factors associated with diagnosis of long COVID syndrome (LCS). Data of 20,601 COVID-19-positive children aged 5 to 18 years were collected between 2020 and 2021 in an Israeli database. Logistic regression analysis was used to evaluate the adjusted odds ratio for the characteristics of the COVID-19 infection and pre-COVID-19 morbidities. Children with LCS were significantly more likely to have been severely symptomatic, required hospitalization, and experienced recurrent acute infection within 180 days. In addition, children with LCS were significantly more likely to have had ADHD, chronic urticaria, and allergic rhinitis. Diagnosis of LCS is significantly associated with pre-COVID-19 ADHD diagnosis, suggesting clinicians treating ADHD children who become infected with COVID-19 remain vigilant for the possibility of LCS. Although the risk of severe COVID-19 infection and LCS in children is low, further research on possible morbidity related to LCS in children is needed.
KW - ADHD
KW - COVID-19
KW - long COVID
KW - morbidity
UR - http://www.scopus.com/inward/record.url?scp=85129804594&partnerID=8YFLogxK
U2 - 10.3390/ijerph19105993
DO - 10.3390/ijerph19105993
M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???
AN - SCOPUS:85129804594
SN - 1661-7827
VL - 19
JO - International Journal of Environmental Research and Public Health
JF - International Journal of Environmental Research and Public Health
IS - 10
M1 - 5993
ER -