Chlamydial IgG and IgA in serum and follicular fluid among patients undergoing in vitro fertilisation

E. Lunenfeld; B. Sarov; I. Sarov; G. Potashnik; S. Albotiano; B. S. Shapiro; A. H. Decherney; V. Insler

doi:10.1016/0028-2243(90)90109-E

Chlamydial IgG and IgA in serum and follicular fluid among patients undergoing in vitro fertilisation

E. Lunenfeld, B. Sarov, I. Sarov, G. Potashnik, S. Albotiano, B. S. Shapiro, A. H. Decherney, V. Insler

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Abstract

The point prevalence of IgG and IgA antibodies to Chlamydia was analyzed in serum and follicular fluid in 63 patients undergoing in vitro fertilisation (IVF) in comparison to sera of 298 healthy women by the single serovar (L2) inclusion immunoperoxidase assay (IPA). The presence of specific IgG and IgA to Chlamydia in follicular fluid was demonstrated. No statistical association was found between the presence of specific Chlamydia IgG and IgA in serum and follicular fluid to oocyte fertilization. The positive predictive value for mechanical infertility of Chlamydia IgG at titers of ≥ 128 and IgA titers at ≥ 16 was 91 and 92%, respectively, in this high-risk group for mechanical infertility. Multiple regression analysis singled out Chlamydia IgG levels as a major contributor to the variance between the groups of infertile patients.

Original language	English
Pages (from-to)	163-173
Number of pages	11
Journal	European Journal of Obstetrics, Gynecology and Reproductive Biology
Volume	37
Issue number	2
DOIs	https://doi.org/10.1016/0028-2243(90)90109-E
State	Published - Nov 1990
Externally published	Yes

Keywords

Chlamydia
IgG and IgA antibody
In vitro fertilisation
Infertility

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10.1016/0028-2243(90)90109-E

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title = "Chlamydial IgG and IgA in serum and follicular fluid among patients undergoing in vitro fertilisation",

abstract = "The point prevalence of IgG and IgA antibodies to Chlamydia was analyzed in serum and follicular fluid in 63 patients undergoing in vitro fertilisation (IVF) in comparison to sera of 298 healthy women by the single serovar (L2) inclusion immunoperoxidase assay (IPA). The presence of specific IgG and IgA to Chlamydia in follicular fluid was demonstrated. No statistical association was found between the presence of specific Chlamydia IgG and IgA in serum and follicular fluid to oocyte fertilization. The positive predictive value for mechanical infertility of Chlamydia IgG at titers of ≥ 128 and IgA titers at ≥ 16 was 91 and 92%, respectively, in this high-risk group for mechanical infertility. Multiple regression analysis singled out Chlamydia IgG levels as a major contributor to the variance between the groups of infertile patients.",

keywords = "Chlamydia, IgG and IgA antibody, In vitro fertilisation, Infertility",

author = "E. Lunenfeld and B. Sarov and I. Sarov and G. Potashnik and S. Albotiano and Shapiro, {B. S.} and Decherney, {A. H.} and V. Insler",

year = "1990",

month = nov,

doi = "10.1016/0028-2243(90)90109-E",

language = "אנגלית",

volume = "37",

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journal = "European Journal of Obstetrics, Gynecology and Reproductive Biology",

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T1 - Chlamydial IgG and IgA in serum and follicular fluid among patients undergoing in vitro fertilisation

AU - Lunenfeld, E.

AU - Sarov, B.

AU - Sarov, I.

AU - Potashnik, G.

AU - Albotiano, S.

AU - Shapiro, B. S.

AU - Decherney, A. H.

AU - Insler, V.

PY - 1990/11

Y1 - 1990/11

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AB - The point prevalence of IgG and IgA antibodies to Chlamydia was analyzed in serum and follicular fluid in 63 patients undergoing in vitro fertilisation (IVF) in comparison to sera of 298 healthy women by the single serovar (L2) inclusion immunoperoxidase assay (IPA). The presence of specific IgG and IgA to Chlamydia in follicular fluid was demonstrated. No statistical association was found between the presence of specific Chlamydia IgG and IgA in serum and follicular fluid to oocyte fertilization. The positive predictive value for mechanical infertility of Chlamydia IgG at titers of ≥ 128 and IgA titers at ≥ 16 was 91 and 92%, respectively, in this high-risk group for mechanical infertility. Multiple regression analysis singled out Chlamydia IgG levels as a major contributor to the variance between the groups of infertile patients.

KW - Chlamydia

KW - IgG and IgA antibody

KW - In vitro fertilisation

KW - Infertility

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JF - European Journal of Obstetrics, Gynecology and Reproductive Biology

IS - 2

ER -

Chlamydial IgG and IgA in serum and follicular fluid among patients undergoing in vitro fertilisation

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Keywords

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