Changes in serum magnesium concentration after strenuous exercise

Gustawa Stendig Lindberg, Yair Shapiro, Yoram Epstein, Eitan Galun, Emil Schonberger, Eran Graff, Warren E.C. Wacker

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Serum magnesium concentration (S-Mg) was measured in 20 highly trained young men (mean age 19.5, ± 0.5, range 18-20.5) before, and at 1 hour, 24 hours, 72 hours, and 3 months after a 120 km hike. As found in previous studies, S-Mg was significantly decreased at the end of the hike (p < 0.001); Student’s t-test). In this group S-Mg had risen significantly after 24 hours in relation to the value at 1 hour (but not to starting value); yet, at 72 hours and 3 months later, it was once more significantly lower than the starting value (p < 0.001 and p < 0.05, respectively, Student’s t-test). A marked elevation in serum creatine kinase activity (CK) suggests that the rise in S-Mg observed at 24 hours is the result of either exertional rhabdomyolysis or loss of membrane integrity, as a result of the strenuous exertion, since the CK had fallen sharply by 72 hours after the hike. The biphasic, statistically significant, lowering of S-Mg which persisted after 3 months suggests that strenuous exertion induces magnesium deficiency.

Original languageEnglish
Pages (from-to)35-40
Number of pages6
JournalJournal of the American College of Nutrition
Issue number1
StatePublished - 1 Jan 1987
Externally publishedYes


  • Calcium (serum)
  • Cretine Kinase
  • Magnesium (serum)
  • Stress


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