C-reactive protein levels in children with primary herpetic gingivostomatitis

Alon Nevet, Havatzelet Yarden-Bilavsky, Shai Ashkenazi, Gilat Livni

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Background: C-reactive protein (CRP) is often used to distinguish bacterial from viral infections. However, the CRP level does have implications, which depend on the clinical scenario and are still under research.

Objectives: To evaluate the distribution of CRP levels in children with primary herpetic gingivostomatitis.

Methods: The electronic database of a tertiary pediatric medical center was searched for all inpatients with a diagnosis of primary herpetic gingivostomatitis without bacterial coinfection.

Background and clinical information was collected and CRP levels were analyzed.

Results: The study group consisted of 66 patients aged 8 months to 7.1 years who met the study criteria. The average CRP was 7.4 mg/dl (normal < 0.5 mg/dl). More than a third of the patients had a level higher than 7 mg/dl.

Conclusions: High values of CRP are prevalent in patients with primary herpetic gingivostomatitis, similar to adenoviral infections and some bacterial infections.

Original languageEnglish
Pages (from-to)700
Number of pages1
JournalIsrael Medical Association Journal
Issue number11
StatePublished - 1 Nov 2014
Externally publishedYes


  • C-reactive protein (CRP)
  • Herpes simplex virus
  • Infection
  • Inflammation
  • Primary herpetic gingivostomatitis


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