TY - JOUR
T1 - Behavioral effects of chemotherapy in children with cancer
AU - Dolgin, Michael J.
N1 - Funding Information:
Aggressive anticancer treatment regimens that are responsible for the improved prognosis of many pediatric malignancies also constitute major sources of iatrogenic distress. Patients often describe painful medical procedures, such as repeated bone marrow aspira- Dr. Dolgin is a Clinical Psychologist, Behavioral Science Section, Division of Hematology-Oncology, Childrens Hospital of Los Angeles, 4650 Sunset Blvd., Los Angeles, CA 90027. The research described in the article was supported by Grant PBR-12 from the National Office of American Cancer Society (ACS) and by Grant P-2-84 from the California Division of ACS. The article is based on a paper delivered at the division's Western Regional Conference on "Psychosocial Issues in Cancer," held in Los Angeles, January 30-31, 1987. The author wishes to acknowledge his co-investigator, Ernest R. Katz, PhD, and research staff members Betsy Yachzel, PhD, Hilda Kwok, PhD, Mari Radzik, MA, and Robyn Steer, MA.
PY - 1989/3/29
Y1 - 1989/3/29
N2 - Chemotherapy-related distress constitutes a medical and psychosocial management challenge with significant implications for patients’ adjustment to and compliance with anticancer therapy. Because of wide interpatient variability in levels of distress before and after chemotherapy, identifying the treatment and patient variables that act as risk factors for aversive reactions has become important. This article discusses the scope and determinants of chemotherapy-related nausea, vomiting, and behavioral distress in pediatric cancer patients, with special attention to anticipatory symptoms. Findings from a three-year prospective study of distress in children and adolescents receiving chemotherapy are summarized. The value of behavioral assessment studies is considered from the viewpoint of professionals’ ability to design for and target interventions selectively to patients who are at greatest risk.
AB - Chemotherapy-related distress constitutes a medical and psychosocial management challenge with significant implications for patients’ adjustment to and compliance with anticancer therapy. Because of wide interpatient variability in levels of distress before and after chemotherapy, identifying the treatment and patient variables that act as risk factors for aversive reactions has become important. This article discusses the scope and determinants of chemotherapy-related nausea, vomiting, and behavioral distress in pediatric cancer patients, with special attention to anticipatory symptoms. Findings from a three-year prospective study of distress in children and adolescents receiving chemotherapy are summarized. The value of behavioral assessment studies is considered from the viewpoint of professionals’ ability to design for and target interventions selectively to patients who are at greatest risk.
UR - http://www.scopus.com/inward/record.url?scp=0024522535&partnerID=8YFLogxK
U2 - 10.1300/J077v06n03_07
DO - 10.1300/J077v06n03_07
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AN - SCOPUS:0024522535
SN - 0734-7332
VL - 6
SP - 99
EP - 107
JO - Journal of Psychosocial Oncology
JF - Journal of Psychosocial Oncology
IS - 3-4
ER -