Around the model of infection disease: The Cauchy matrix and its properties

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In this paper the model of infection diseases by Marchuk is considered. Mathematical questions which are important in its study are discussed. Among them there are stability of stationary points, construction of the Cauchy matrices of linearized models, estimates of solutions. The novelty we propose is in a distributed feedback control which affects the antibody concentration. We use this control in the form of an integral term and come to the analysis of nonlinear integro-differential systems. New methods for the study of stability of linearized integro-differential systems describing the model of infection diseases are proposed. Explicit conditions of the exponential stability of the stationary points characterizing the state of the healthy body are obtained. The method of the paper is based on the symmetry properties of the Cauchy matrices which allow us their construction.

Original languageEnglish
Article number1016
Issue number8
StatePublished - 2019


  • Cauchy matrix
  • Distributed control
  • Exponential stability
  • Integro-differential systems


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