Antigen of erythroblast (Ag-Eb): A membrane protein that may be an erythroid-specific transferrin receptor

V. Fukson; M. Kostyukov; V. Toder; J. S. Irlin; M. A. Firer

doi:10.1054/mehy.1998.0803

Antigen of erythroblast (Ag-Eb): A membrane protein that may be an erythroid-specific transferrin receptor

V. Fukson, M. Kostyukov, V. Toder, J. S. Irlin, M. A. Firer

Research output: Contribution to journal › Article › peer-review

Abstract

Only a limited number of erythroid cell surface markers have been described in the literature. Ag-Eb was originally described as an erythroid-specific cell surface glycoprotein and could be used as an erythroid differentiation marker, but more recent studies suggest this localization is more widespread. From the data summarized in this review, it is hypothesized that Ag-Eb is a member of a subset of the transferrin receptor family and that it functions together with these receptors in the uptake and metabolism of iron, particularly at histo-hematic barriers. (C) 2000 Harcourt Publishers Ltd.

Original language	English
Pages (from-to)	107-114
Number of pages	8
Journal	Medical Hypotheses
Volume	54
Issue number	1
DOIs	https://doi.org/10.1054/mehy.1998.0803
State	Published - Jan 2000

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abstract = "Only a limited number of erythroid cell surface markers have been described in the literature. Ag-Eb was originally described as an erythroid-specific cell surface glycoprotein and could be used as an erythroid differentiation marker, but more recent studies suggest this localization is more widespread. From the data summarized in this review, it is hypothesized that Ag-Eb is a member of a subset of the transferrin receptor family and that it functions together with these receptors in the uptake and metabolism of iron, particularly at histo-hematic barriers. (C) 2000 Harcourt Publishers Ltd.",

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Antigen of erythroblast (Ag-Eb): A membrane protein that may be an erythroid-specific transferrin receptor

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