Amplification of enantiomeric concentrations under credible prebiotic conditions

Ronald Breslow, Mindy S. Levine

Research output: Contribution to journalArticlepeer-review

117 Scopus citations


Solutions with as little as 1% enantiomeric excess (ee) of D- or L-phenylalanine are amplified to 90% ee (a 95/5 ratio) by two successive evaporations to precipitate the racemate. Such a process on the prebiotic earth could lead to a mechanism by which meteoritic chiral α-alkyl amino acids could form solutions with high ee values that were needed for the beginning of biology.

Original languageEnglish
Pages (from-to)12979-12980
Number of pages2
JournalProceedings of the National Academy of Sciences of the United States of America
Issue number35
StatePublished - 29 Aug 2006
Externally publishedYes


  • Amino acids
  • Crystallization
  • Transamination


Dive into the research topics of 'Amplification of enantiomeric concentrations under credible prebiotic conditions'. Together they form a unique fingerprint.

Cite this