Amplification of enantiomeric concentrations under credible prebiotic conditions

Ronald Breslow, Mindy S. Levine

Research output: Contribution to journalArticlepeer-review

121 Scopus citations

Abstract

Solutions with as little as 1% enantiomeric excess (ee) of D- or L-phenylalanine are amplified to 90% ee (a 95/5 ratio) by two successive evaporations to precipitate the racemate. Such a process on the prebiotic earth could lead to a mechanism by which meteoritic chiral α-alkyl amino acids could form solutions with high ee values that were needed for the beginning of biology.

Original languageEnglish
Pages (from-to)12979-12980
Number of pages2
JournalProceedings of the National Academy of Sciences of the United States of America
Volume103
Issue number35
DOIs
StatePublished - 29 Aug 2006
Externally publishedYes

Keywords

  • Amino acids
  • Crystallization
  • Transamination

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