TY - JOUR
T1 - Agonal elevation in serum digoxin concentrations in infants and children long after cessation of therapy
AU - Koren, G.
AU - Beatie, D.
AU - Soldin, S.
PY - 1988
Y1 - 1988
N2 - In 11 of 15 profoundly sick, digitalized infants and children, elevation in serum digoxin concentration could be detected long after cessation of therapy. This phenomenon concurred with a rapid deterioration of renal function. Because death of a digitalized child may be attributed to the glycoside itself, it is important to recognize that elevation in serum concentration to a potentially toxic level is a common pathophysiologic pattern.
AB - In 11 of 15 profoundly sick, digitalized infants and children, elevation in serum digoxin concentration could be detected long after cessation of therapy. This phenomenon concurred with a rapid deterioration of renal function. Because death of a digitalized child may be attributed to the glycoside itself, it is important to recognize that elevation in serum concentration to a potentially toxic level is a common pathophysiologic pattern.
UR - http://www.scopus.com/inward/record.url?scp=0023695614&partnerID=8YFLogxK
U2 - 10.1097/00003246-198808000-00013
DO - 10.1097/00003246-198808000-00013
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C2 - 3396374
AN - SCOPUS:0023695614
SN - 0090-3493
VL - 16
SP - 793
EP - 795
JO - Critical Care Medicine
JF - Critical Care Medicine
IS - 8
ER -