TY - JOUR
T1 - Acute Resin Phenol-formaldehyde Intoxication. A Life Threatening Occupational Hazard
AU - Cohen, N.
AU - Modai, D.
AU - Khahil, A.
AU - Golik, A.
PY - 1989/5
Y1 - 1989/5
N2 - 1 A 38-year-old previously healthy worker accidentally spilled phenol-formaldehyde resin over a large area of his skin. 2 Several days later he was hospitalized with extensive necrotic skin lesions, fever, hypertension, adult respiratory distress syndrome (ARDS), proteinuria and renal functional impairment. 3 All symptoms improved progressively and eventually disappeared. 4 We propose that toxic materials originating from the necrotic skin lesions and the continued facilitated absorption of the resin and/or its components via the skin lesions were the main factors responsible for this alarming multisystem involvement. 5 Workers handling this material should be instructed to take appropriate precautions and physicians should be alerted to the potential pathophysiological consequences.
AB - 1 A 38-year-old previously healthy worker accidentally spilled phenol-formaldehyde resin over a large area of his skin. 2 Several days later he was hospitalized with extensive necrotic skin lesions, fever, hypertension, adult respiratory distress syndrome (ARDS), proteinuria and renal functional impairment. 3 All symptoms improved progressively and eventually disappeared. 4 We propose that toxic materials originating from the necrotic skin lesions and the continued facilitated absorption of the resin and/or its components via the skin lesions were the main factors responsible for this alarming multisystem involvement. 5 Workers handling this material should be instructed to take appropriate precautions and physicians should be alerted to the potential pathophysiological consequences.
UR - http://www.scopus.com/inward/record.url?scp=84973751494&partnerID=8YFLogxK
U2 - 10.1177/096032718900800308
DO - 10.1177/096032718900800308
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C2 - 2744783
AN - SCOPUS:84973751494
SN - 0960-3271
VL - 8
SP - 247
EP - 250
JO - Human and Experimental Toxicology
JF - Human and Experimental Toxicology
IS - 3
ER -