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ABSTRACT The relation between infections and autoimmune diseases has been extensively investigated. Multiple studies suggest a causal relation between these two entities with molecular mimicry, hyperstimulation and dysregulation of the immune system as plausible mechanisms. The recent pandemic with a new virus, i.e., SARS-CoV-2, has resulted in numerous studies addressing the potential of this virus to induce autoimmunity and, eventually, autoimmune disease. In addition, it has also revealed that pre-existing auto-immunity (auto-Abs neutralizing type I IFNs) could cause life-threatening disease. Therefore, the topic of the 15th Dresden Sympo toantibodies was focused on autoimmunity in the SARS-CoV-2 era. This report is a collection and distillation of the topics presented at this meeting. The spectrum from association to clinical implication: Report of the 15th Dresden Symposium on Autoantibodies

  • Jan Damoiseaux
  • , Arad Dotan
  • , Marvin J. Fritzler
  • , Dimitrios P. Bogdanos
  • , Pier Luigi Meroni
  • , Dirk Roggenbuck
  • , Michel Goldman
  • , Nils Landegren
  • , Paul Bastard
  • , Yehuda Shoenfeld
  • , Karsten Conrad

Research output: Contribution to journal › Article › peer-review

77 Scopus citations

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Dive into the research topics of 'ABSTRACT The relation between infections and autoimmune diseases has been extensively investigated. Multiple studies suggest a causal relation between these two entities with molecular mimicry, hyperstimulation and dysregulation of the immune system as plausible mechanisms. The recent pandemic with a new virus, i.e., SARS-CoV-2, has resulted in numerous studies addressing the potential of this virus to induce autoimmunity and, eventually, autoimmune disease. In addition, it has also revealed that pre-existing auto-immunity (auto-Abs neutralizing type I IFNs) could cause life-threatening disease. Therefore, the topic of the 15th Dresden Sympo toantibodies was focused on autoimmunity in the SARS-CoV-2 era. This report is a collection and distillation of the topics presented at this meeting. The spectrum from association to clinical implication: Report of the 15th Dresden Symposium on Autoantibodies'. Together they form a unique fingerprint.
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Immunology and Microbiology