When potent teratogens are irreplaceable drugs: Lessons of thalidomide and isotretinoin

Keyphrases

• Teratogen 100%
• Isotretinoin 100%
• Thalidomide 100%
• Teratogenic 57%
• Serum Concentration 28%
• Female Patients 28%
• Contraception 28%
• In Utero Exposure 14%
• Patient Education 14%
• Teratogenicity 14%
• Pharmaceutical Companies 14%
• Teratogenic Effects 14%
• Women of Reproductive Age 14%
• Serum Levels 14%
• Drug Therapy 14%
• Patient Compliance 14%
• Number of Females 14%
• Therapeutic Agents 14%
• Non-pregnant Women 14%
• Lessons Learned 14%
• Women's Needs 14%
• Therapeutic Potential 14%
• Clinical Experience 14%
• Pharmacokinetic Variability 14%
• Birth Control 14%
• Complete Removal 14%
• Drug Elimination 14%
• Successful Development 14%
• Isotretinoin Therapy 14%
• Pregnancy Prevention Program 14%
• Etretinate 14%

Pharmacology, Toxicology and Pharmaceutical Science

• Teratogenic Agent 100%
• Isotretinoin 100%
• Thalidomide 100%
• Elimination 14%
• Teratogenicity 14%
• Drug 14%
• Chemical Teratogen 14%
• Pharmacotherapy 14%
• Etretinate 14%
• Pharmacokinetics 14%