TY - JOUR
T1 - Unintended pregnancy during radiotherapy for cancer
AU - de Wildt, Saskia N.
AU - Taguchi, Nobuko
AU - Koren, Gideon
N1 - Funding Information:
SN de Wildt’s research is supported by a Ter Meulen Fund stipend from the Royal Netherlands Academy of Research, and a Restracomp grant from the Hospital for Sick Children, Toronto, Canada. N Taguchi’s research is supported by the Aiiku Imperial Fund in Japan, and a Restracomp grant from the Hospital for Sick Children. G Koren is supported by the Research Leadership for Better Pharmacotherapy during Pregnancy and Lactation at the University of Toronto, and is a holder of the Ivey Chair in Molecular Toxicology, at the University of Western Ontario, Canada.
PY - 2009
Y1 - 2009
N2 - Background: A 27-year-old woman with upper mediastinum stage IIA Hodgkin lymphoma was treated with six cycles of doxorubicin, bleomycin, vinblastine, and dacarbazine chemotherapy. Two months later she received a total of 4,250 cGy to the upper mediastinum and left clavicular region over a 1-month period. One week after completion of radiotherapy she was found to be 13-weeks pregnant. Her physician advised her to terminate pregnancy. She contacted a teratology information service for further information regarding the risks of radiation exposure for her fetus. Investigations: Estimation of fetal radiation exposure, literature review and synthesis of published cases and effects of fetal radiation exposure. Diagnosis: Estimated fetal radiation dose between 5 and 18 cGy. Management: Counseling on the possible risks to the fetus as a result of radiation exposure.
AB - Background: A 27-year-old woman with upper mediastinum stage IIA Hodgkin lymphoma was treated with six cycles of doxorubicin, bleomycin, vinblastine, and dacarbazine chemotherapy. Two months later she received a total of 4,250 cGy to the upper mediastinum and left clavicular region over a 1-month period. One week after completion of radiotherapy she was found to be 13-weeks pregnant. Her physician advised her to terminate pregnancy. She contacted a teratology information service for further information regarding the risks of radiation exposure for her fetus. Investigations: Estimation of fetal radiation exposure, literature review and synthesis of published cases and effects of fetal radiation exposure. Diagnosis: Estimated fetal radiation dose between 5 and 18 cGy. Management: Counseling on the possible risks to the fetus as a result of radiation exposure.
UR - https://www.scopus.com/pages/publications/73949109360
U2 - 10.1038/ncponc1320
DO - 10.1038/ncponc1320
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C2 - 19174775
AN - SCOPUS:73949109360
SN - 1743-4254
VL - 6
SP - 175
EP - 178
JO - Nature Clinical Practice Oncology
JF - Nature Clinical Practice Oncology
IS - 3
ER -