The Fetal Safety of Hydrocortisone-Pramoxine (Proctofoam-HC) for the Treatment of Hemorrhoids in Late Pregnancy

Neda Ebrahimi, Sabina Vohra, Christelle Gedeon, Hani Akoury, Paul Bernstein, Nicholas Pairaudeau, Johanne Cormier, Lorraine Dontigny, Marc Yvon Arsenault, Claude Fortin, Martine Goyet, Chantal Lafortune, Johanne Lalande, Coralie Beauchamp, Francis Engel, Anne Fortin, Anna Taddio, Tom Einarson, Gideon Koren

نتاج البحث: نشر في مجلةمقالةمراجعة النظراء

20 اقتباسات (Scopus)

ملخص

Objective: Fetal safety has never been studied for any drug used in the treatment of hemorrhoids. Proctofoam-HC is a combination of a corticosteroid and a local anaesthetic that is proven effective for the treatment of hemorrhoids. The objective of this study was to assess prospectively the fetal safety of third trimester exposure to Proctofoam-HC. Methods: In a multicentre study, 240 women exposed to Proctofoam-HC in the third trimester and a similar number of control pregnant women were followed up postnatally. Results: When compared to controls exposure to Proctofoam-HC was not associated with any adverse fetal effects on birth weight, gestational age, rates of prematurity, or pre- or postnatal complications. Conclusion: Proctofoam-HC is safe to use in the treatment of hemorrhoids in late pregnancy.

اللغة الأصليةالإنجليزيّة
الصفحات (من إلى)153-158
عدد الصفحات6
دوريةJournal of Obstetrics and Gynaecology Canada
مستوى الصوت33
رقم الإصدار2
المعرِّفات الرقمية للأشياء
حالة النشرنُشِر - 2011
منشور خارجيًانعم

بصمة

أدرس بدقة موضوعات البحث “The Fetal Safety of Hydrocortisone-Pramoxine (Proctofoam-HC) for the Treatment of Hemorrhoids in Late Pregnancy'. فهما يشكلان معًا بصمة فريدة.

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